Agreement analysis of LENSTAR with other techniques of biometry

Eye (Lond). 2011 Jun;25(6):717-24. doi: 10.1038/eye.2011.28. Epub 2011 Mar 11.


Purpose: To assess the agreement of the optical low-coherence reflectometry (OLCR) device LENSTAR LS900 with partial coherence interferometry (PCI) device IOLMaster and applanation and immersion ultrasound biometry.

Methods: We conducted the study at the Ophthalmology Clinic, University of Malaya Medical Center, Malaysia. Phakic eyes of 76 consecutive cataract patients were measured using four different methods: IOLMaster, LENSTAR and A-scan applanation and immersion ultrasound biometry. We assessed the method agreement in the LENSTAR-IOLMaster, LENSTAR-applanation, and LENSTAR-immersion comparisons for axial length (AL) and intraocular lens (IOL) power using Bland-Altman plots. For average K, we compared LENSTAR with IOLMaster and the TOPCON KR-8100 autorefractor-keratometer. SRK/T formula was used to compute IOL power, with emmetropia as the target refractive outcome.

Results: For all the variables studied, LENSTAR agreement with IOLMaster is strongest, followed by those with immersion and applanation. For the LENSTAR-IOLMaster comparison, the estimated proportion of differences falling within 0.33 mm from zero AL and within 1D from zero IOL power is 100%. The estimated proportion of differences falling within 0.5 D from zero average K is almost 100% in the LENSTAR-IOLMaster comparison but 88% in the LENSTAR-TOPCON comparison. The proportion of differences falling within 0.10 mm (AL) and within 1D (IOL power) in the LENSTAR-IOLMaster comparison has practically significant discrepancy with that of LENSTAR-applanation and LENSTAR-immersion comparisons.

Conclusions: In phakic eyes of cataract patients, measurements of AL, average K, and IOL power calculated using the SRK/T formula from LENSTAR are biometrically equivalent to those from IOLMaster, but not with those from applanation and immersion ultrasound biometry.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Anterior Chamber / pathology
  • Aphakia, Postcataract / physiopathology*
  • Axial Length, Eye
  • Biometry
  • Diagnostic Techniques, Ophthalmological*
  • Female
  • Humans
  • Interferometry / methods
  • Lenses, Intraocular*
  • Male
  • Middle Aged
  • Optics and Photonics / methods*
  • Young Adult