Complete remission of renal cell carcinoma with lung metastases in two hemodialysis patients after low-dose interferon therapy

Hemodial Int. 2011 Apr;15(2):288-92. doi: 10.1111/j.1542-4758.2011.00540.x. Epub 2011 Mar 13.

Abstract

A standard immunotherapy strategy for metastatic renal cell carcinoma (RCC) in dialysis patients has yet to be established. In this study, we report complete remission of RCC with lung metastases in 2 hemodialysis patients after low-dose interferon therapy (Sumiferon® 3 × 10⁶ international unit 3 times a week). These results suggest that interferon therapy is important for clear cell RCC with lung metastases in dialysis patients, even in the era of molecular-targeted therapies.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Carcinoma, Renal Cell / drug therapy*
  • Carcinoma, Renal Cell / surgery
  • Humans
  • Interferon-alpha / administration & dosage*
  • Kidney Neoplasms / drug therapy*
  • Kidney Neoplasms / surgery
  • Lung Neoplasms / drug therapy*
  • Lung Neoplasms / secondary*
  • Male
  • Middle Aged
  • Neoplasm Metastasis
  • Remission Induction
  • Renal Dialysis*

Substances

  • Interferon-alpha