Bubble continuous positive airway pressure in a human immunodeficiency virus-infected infant

Int J Tuberc Lung Dis. 2011 Apr;15(4):562-4. doi: 10.5588/ijtld.10.0583.


World Health Organization-classified very severe pneumonia due to Pneumocystis jirovecii infection is recognized as a life-threatening condition in human immunodeficiency virus (HIV) infected infants. We recount the use of nasal bubble continuous positive airway pressure (BCPAP) in an HIV-infected African infant with very severe pneumonia and treatment failure due to suspected infection with P. jirovecii. We also examine the potential implications of BCPAP use in resource-poor settings with a high case index of acute respiratory failure due to HIV-related pneumonia, but limited access to mechanical ventilation.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural

MeSH terms

  • AIDS-Related Opportunistic Infections / microbiology
  • AIDS-Related Opportunistic Infections / therapy
  • Continuous Positive Airway Pressure / methods*
  • HIV Infections / complications
  • HIV Infections / therapy*
  • Humans
  • Infant
  • Malawi
  • Male
  • Pneumocystis carinii / isolation & purification*
  • Pneumonia, Pneumocystis / microbiology
  • Pneumonia, Pneumocystis / therapy*
  • Severity of Illness Index
  • Treatment Failure