Evaluation of the Xpert® group B streptococcus real-time polymerase chain reaction assay compared to StrepB Carrot Broth™ for the rapid intrapartum detection of group B streptococcus colonization

Diagn Microbiol Infect Dis. 2011 Apr;69(4):460-2. doi: 10.1016/j.diagmicrobio.2010.11.002.


Xpert group B streptococcus (GBS) was compared to StrepB Carrot Broth™ (SCB) for the detection of intrapartum GBS colonization by dually collecting vaginal/rectal swabs from 231 women. Xpert GBS detected all of the cases (45, 19.5%), but 4 were missed by SCB. A rapid Xpert GBS service for women in labor would increase costs by ∼$55.000 per annum in our region.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Bacteriological Techniques / methods*
  • Carrier State / diagnosis
  • Carrier State / microbiology*
  • Female
  • Humans
  • Mass Screening
  • Parturition
  • Polymerase Chain Reaction / methods*
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis
  • Pregnancy Complications, Infectious / microbiology*
  • Sensitivity and Specificity
  • Streptococcus agalactiae / genetics
  • Streptococcus agalactiae / isolation & purification*