Moyamoya disease in early infancy: case report and literature review

Pediatr Neurol. 2011 Apr;44(4):299-302. doi: 10.1016/j.pediatrneurol.2010.10.016.


Moyamoya disease is a progressive, occlusive, cerebrovascular arteriopathy, characterized by bilateral stenosis of the distal internal carotid arteries or branches, with the development of compensatory collateral vessels. It is infrequently reported during infancy. We describe a 2-month-old boy presenting with stroke secondary to moyamoya disease, successfully treated with revascularization surgery at age 3 months. To our knowledge, this report represents the youngest such patient. This case and a review of the literature regarding moyamoya disease during infancy suggest that these patients are at significant risk for further ischemic events and respond well to prompt revascularization surgery.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Carotid Arteries / diagnostic imaging
  • Carotid Arteries / pathology
  • Coronary Angiography / methods
  • Humans
  • Infant
  • Male
  • Moyamoya Disease* / diagnosis
  • Moyamoya Disease* / surgery