Perilymphatic subcutaneous fat atrophy and cutaneous depigmentation after periocular triamcinolone acetonide injection in a child

Abstract

Periocular corticosteroid injection is a potent and versatile treatment for uveitic conditions as well as for some ocular tumors. Despite its efficacy, ophthalmologists are wary of documented side effects, some of which can be blinding. Adverse reactions are mostly dependent on route of administration, with glaucoma and cataract formation more often seen in peribulbar and intraocular injections, whereas skin depigmentation and fat atrophy are more frequently related to intradermal or intralesional routes, particularly after injection of capillary hemangioma of infancy. We present a child with perilymphatic linear subcutaneous fat atrophy and depigmentation after sub-Tenon's fascia injection of triamcinolone acetonide.