Genome sequences of two Staphylococcus aureus ovine strains that induce severe (strain O11) and mild (strain O46) mastitis

J Bacteriol. 2011 May;193(9):2353-4. doi: 10.1128/JB.00045-11. Epub 2011 Mar 11.

Abstract

Staphylococcus aureus is a major etiological agent of mastitis in ruminants. We report here the genome sequences of two ovine strains that were isolated from gangrenous (strain O11) and subclinical (strain O46) ewe mastitis. Both strains belong to the same clonal complex. Despite this close genotypic relationship, the two isolates were shown to reproducibly induce highly divergent types of infections, either severe (O11) or mild (O46) mastitis, in an experimental ewe model.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Female
  • Genome, Bacterial*
  • Mastitis / microbiology
  • Mastitis / veterinary*
  • Molecular Sequence Data
  • Polymorphism, Single Nucleotide
  • Sheep
  • Sheep Diseases / microbiology*
  • Staphylococcus aureus / classification*
  • Staphylococcus aureus / genetics*

Associated data

  • GENBANK/AEUQ01000000
  • GENBANK/AEUR01000000