Central serous chorioretinopathy as a presenting symptom of endogenous Cushing syndrome: a case report

Eur J Ophthalmol. 2011 Sep-Oct;21(5):661-4. doi: 10.5301/EJO.2011.6449.


Purpose: To report a case of Cushing syndrome due to adrenocortical adenoma revealed by central serous chorioretinopathy.

Materials and methods: A 45-year-old man presented with blurred vision and metamorphopsia in the left eye. He reported few episodes of high blood pressure in the last 3 months.

Results: Visual acuity was 20/40 in the left eye. Fundus oculi examination revealed central serous chorioretinopathy in the left eye. Grade 1 hypertension was found. Increased serum and urinary levels of cortisol and reduced serum levels of ACTH were observed. Diagnosis of Cushing syndrome was made. Computed tomography scan revealed a right adrenal mass that was surgically removed; histologic examination showed an adrenocortical adenoma. Three months after surgical treatment, visual acuity improved to 20/20 and central serous chorioretinopathy completely resolved.

Conclusions: Central serous chorioretinopathy may be the presenting symptom of Cushing syndrome in a patient with adrenocortical adenoma.

Publication types

  • Case Reports

MeSH terms

  • Adenoma / diagnostic imaging
  • Adenoma / pathology*
  • Adenoma / surgery
  • Adrenal Cortex Neoplasms / diagnostic imaging
  • Adrenal Cortex Neoplasms / pathology*
  • Adrenal Cortex Neoplasms / surgery
  • Adrenocorticotropic Hormone / blood
  • Central Serous Chorioretinopathy / blood
  • Central Serous Chorioretinopathy / diagnosis*
  • Central Serous Chorioretinopathy / urine
  • Cushing Syndrome / blood
  • Cushing Syndrome / diagnosis*
  • Cushing Syndrome / urine
  • Humans
  • Hydrocortisone / blood
  • Hydrocortisone / urine
  • Hypertension / diagnosis
  • Male
  • Middle Aged
  • Tomography, X-Ray Computed
  • Vision Disorders / diagnosis
  • Visual Acuity


  • Adrenocorticotropic Hormone
  • Hydrocortisone