[Continuous low volume infusion of hydroxyethyl starch as an option of water balance correction in patients with gestosis]

Anesteziol Reanimatol. 2010 Nov-Dec:(6):68-71.
[Article in Russian]


The method of long-term continuous low-volume infusion of hydroxyethyl starch (low-flow low volume correction HES) is administrated for correction of fluid balance disorders. The method is aimed to improve the outcomes in preeclamsia patients with multiple organ dysfunction and failure, as the most severe manifestation of system inflammatory response syndrome. After 4 days of the intensive care with application of the developed method in patients with preeclamsia the total body water level is decreased to the normal physiological level, the oedemas are significantly reduced or ceased, the haemodynamics stabilizes, which leads to the reduce of neurologic symptoms. The suggested method of low-flow low volume correction HES, in dose of 15 ml/kg/day is a significant addition to the existing methods of homeostasis and preeclampsia correction.

Publication types

  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Blood Proteins / metabolism
  • Capillary Leak Syndrome / prevention & control
  • Female
  • Hemodynamics / physiology
  • Humans
  • Hydroxyethyl Starch Derivatives / administration & dosage*
  • Hypertonic Solutions
  • Infusions, Intravenous
  • Long-Term Care
  • Osmolar Concentration
  • Plasma Substitutes / administration & dosage*
  • Pre-Eclampsia / metabolism
  • Pre-Eclampsia / physiopathology
  • Pre-Eclampsia / therapy*
  • Pregnancy
  • Treatment Outcome
  • Water-Electrolyte Balance*
  • Young Adult


  • Blood Proteins
  • Hydroxyethyl Starch Derivatives
  • Hypertonic Solutions
  • Plasma Substitutes