Resin infiltration of proximal caries lesions differing in ICDAS codes

Eur J Oral Sci. 2011 Apr;119(2):182-6. doi: 10.1111/j.1600-0722.2011.00807.x. Epub 2011 Mar 3.


Resin infiltration of non-cavitated proximal caries lesions has been shown to inhibit further demineralization. However, the effect of resin infiltration in cavitated lesions is unknown. Therefore, the aim of this in vitro study was to evaluate infiltration patterns of proximal caries lesions differing in International Caries Detection and Assessment System (ICDAS) codes. Extracted human molars and premolars showing proximal caries lesions with and without cavitations (ICDAS codes 2-5) were etched with 15% hydrochloric acid gel and resin infiltrated according to the manufacturer's instructions. Three sections from each lesion were prepared and analyzed using a dual-fluorescence staining technique and confocal microscopy. The dimensions of the demineralized and cavitated lesions areas, as well as the resin-infiltrated parts within these lesions, were measured. The demineralized parts were infiltrated from 73% to 100% (median values) but the cavities were filled only negligibly (0-5%). Teeth that had an ICDAS code of 5 showed a significantly lower percentage infiltration/filling of lesions compared to teeth with ICDAS codes of 2 and 3. It was concluded that under in vitro conditions the tested infiltrant penetrates most parts of the demineralized enamel but is not capable of filling up cavities and therefore the efficacy of caries infiltration, particularly in lesions with larger cavitations, might be impaired.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bicuspid
  • Dental Atraumatic Restorative Treatment / methods*
  • Dental Caries / classification
  • Dental Caries / pathology
  • Dental Caries / therapy*
  • Dental Caries Activity Tests / standards
  • Dental Cavity Preparation / methods
  • Dental Enamel Permeability
  • Dental Marginal Adaptation*
  • Humans
  • Molar
  • Resin Cements / therapeutic use
  • Resins, Synthetic / therapeutic use*
  • Tooth Demineralization / prevention & control*


  • Resin Cements
  • Resins, Synthetic