An unusual treatment for protein losing enteropathy

Congenit Heart Dis. 2011 May-Jun;6(3):253-6. doi: 10.1111/j.1747-0803.2011.00484.x. Epub 2011 Mar 21.


We present the case of a 22-year-old man with a Fontan circulation who suffered from intractable protein losing enteropathy for an 8-year period necessitating several hospital admissions for recurrent pleural effusions and edema. Despite trying several recognized medical therapies to alleviate his protein losing enteropathy, his condition did not improve until the introduction of loperamide for troublesome diarrhea. Following this, his symptoms and serum albumin improved dramatically and he has not required any further hospital admissions at 22 months follow up.

Publication types

  • Case Reports

MeSH terms

  • Antidiarrheals / therapeutic use*
  • Biomarkers / blood
  • Diarrhea / drug therapy*
  • Diarrhea / etiology
  • Fontan Procedure / adverse effects*
  • Humans
  • Loperamide / therapeutic use*
  • Male
  • Protein-Losing Enteropathies / blood
  • Protein-Losing Enteropathies / drug therapy*
  • Protein-Losing Enteropathies / etiology
  • Serum Albumin / metabolism*
  • Treatment Outcome
  • Young Adult


  • Antidiarrheals
  • Biomarkers
  • Serum Albumin
  • Loperamide