A pilot study of mechanical chest compressions with the LUCAS™ device in cardiopulmonary resuscitation

Resuscitation. 2011 Jun;82(6):702-6. doi: 10.1016/j.resuscitation.2011.01.032. Epub 2011 Mar 17.


Aim: The LUCAS™ device has been shown to improve organ perfusion during cardiac arrest in experimental studies. In this pilot study the aim was to compare short-term survival between cardiopulmonary resuscitation (CPR) performed with mechanical chest compressions using the LUCAS™ device and CPR performed with manual chest compressions. The intention was to use the results for power calculation in a larger randomised multicentre trial.

Methods: In a prospective pilot study, from February 1, 2005, to April 1, 2007, 149 patients with out-of hospital cardiac arrest in two Swedish cities were randomised to mechanical chest compressions or standard CPR with manual chest compressions.

Results: After exclusion, the LUCAS and the manual groups contained 75 and 73 patients, respectively. In the LUCAS and manual groups, spontaneous circulation with a palpable pulse returned in 30 and 23 patients (p = 0.30), spontaneous circulation with blood pressure above 80/50 mm Hg remained for at least 5 min in 23 and 19 patients (p = 0.59), the number of patients hospitalised alive >4h were 18 and 15 (p = 0.69), and the number discharged, alive 6 and 7 (p = 0.78), respectively.

Conclusions: In this pilot study of out-of-hospital cardiac arrest patients we found no difference in early survival between CPR performed with mechanical chest compression with the LUCAS™ device and CPR with manual chest compressions. Data have been used for power calculation in a forthcoming multicentre trial.

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Algorithms
  • Cardiopulmonary Resuscitation / instrumentation*
  • Cardiopulmonary Resuscitation / methods*
  • Female
  • Humans
  • Male
  • Out-of-Hospital Cardiac Arrest / therapy*
  • Pilot Projects
  • Prospective Studies