Thrombotic occlusion of an aortic-root xenograft during left ventricular assistance

Tex Heart Inst J. 2011;38(1):66-7.


A 45-year-old man underwent repair of a congenital bicuspid aortic valve and complex aortic-root aneurysm with an aortic-root xenograft. A CentriMag® left ventricular assist device was implanted for cardiac support and was subsequently replaced with a HeartMate II® left ventricular assist device. A day later, the patient was returned to the operating room for control of bleeding, and thrombotic occlusion of the prosthetic aortic valve was detected. The patient underwent thrombus removal, oversewing of the prosthetic valve, and bypass of the left anterior descending coronary artery. This case emphasizes the hazard of bypassing a failed left ventricle with a cardiac assist device after aortic valve replacement, even with a bioprosthesis.

Keywords: Aorta/surgery; aortic arch/surgery; aortic root/surgery; aortic valve replacement; heart valve prosthesis; postoperative complications; thrombosis; ventricle assist devices.

Publication types

  • Case Reports

MeSH terms

  • Aortic Aneurysm / surgery*
  • Aortic Valve / abnormalities
  • Aortic Valve / surgery*
  • Bioprosthesis*
  • Blood Vessel Prosthesis Implantation / adverse effects
  • Blood Vessel Prosthesis Implantation / instrumentation*
  • Blood Vessel Prosthesis*
  • Coronary Artery Bypass
  • Graft Occlusion, Vascular / etiology*
  • Graft Occlusion, Vascular / surgery
  • Heart Valve Prosthesis Implantation / adverse effects
  • Heart Valve Prosthesis Implantation / instrumentation*
  • Heart Valve Prosthesis*
  • Heart-Assist Devices / adverse effects*
  • Humans
  • Male
  • Middle Aged
  • Prosthesis Design
  • Reoperation
  • Thrombosis / etiology*
  • Thrombosis / surgery
  • Transplantation, Heterologous
  • Treatment Outcome