Serum and bronchoalveolar lavage fluid galactomannan assays in patients with pulmonary aspergilloma

Clin Infect Dis. 2011 Apr 1;52(7):e149-52. doi: 10.1093/cid/cir027.

Abstract

The sensitivities of the serum and bronchoalveolar lavage galactomannan (GM) assays in 48 patients with pulmonary aspergilloma were 38% (13 of 34; 95% confidence interval [CI], 22%-56%) and 92% (33 of 36; 95% CI, 78%-98%), respectively. The positivity of serum GM assays was significantly higher in patients with hemoptysis than in those without hemoptysis (52% vs 9%; P=.02).

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Bronchoalveolar Lavage Fluid / chemistry*
  • Clinical Laboratory Techniques / methods*
  • Female
  • Humans
  • Male
  • Mannans / analysis*
  • Middle Aged
  • Pulmonary Aspergillosis / diagnosis*
  • Sensitivity and Specificity
  • Serum / chemistry*

Substances

  • Mannans
  • galactomannan