Advanced MRI in multiple sclerosis: current status and future challenges

Neurol Clin. 2011 May;29(2):357-80. doi: 10.1016/j.ncl.2010.12.011.

Abstract

MRI has rapidly become a leading research tool in the study of multiple sclerosis (MS). Conventional imaging is useful in diagnosis and management of the inflammatory stages of MS but has limitations in describing the degree of tissue injury and cause of progressive disability seen in later stages. Advanced MRI techniques hold promise for filling this void. These imaging tools hold great promise to increase understanding of MS pathogenesis and provide greater insight into the efficacy of new MS therapies.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Brain Mapping
  • Brain* / blood supply
  • Brain* / metabolism
  • Brain* / pathology
  • Diagnostic Imaging* / classification
  • Diagnostic Imaging* / methods
  • Diagnostic Imaging* / trends
  • Humans
  • Image Processing, Computer-Assisted / methods
  • Multiple Sclerosis / diagnosis*
  • Spinal Cord / blood supply
  • Spinal Cord / metabolism
  • Spinal Cord / pathology