Mechanisms of Top-Down Attention

Trends Neurosci. 2011 Apr;34(4):210-24. doi: 10.1016/j.tins.2011.02.003. Epub 2011 Mar 23.

Abstract

Attention exhibits characteristic neural signatures in brain regions that process sensory signals. An important area of future research is to understand the nature of top-down signals that facilitate attentional guidance towards behaviorally relevant locations and features. In this review, we discuss recent studies that have made progress towards understanding: (i) the brain structures and circuits involved in attentional allocation; (ii) top-down attention pathways, particularly as elucidated by microstimulation and lesion studies; (iii) top-down modulatory influences involving subcortical structures and reward systems; (iv) plausible substrates and embodiments of top-down signals; and (v) information processing and theoretical constraints that might be helpful in guiding future experiments. Understanding top-down attention is crucial for elucidating the mechanisms by which we can filter sensory information to pay attention to the most behaviorally relevant events.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Attention / physiology*
  • Brain / anatomy & histology*
  • Brain / physiology*
  • Brain Mapping
  • Computer Simulation
  • Humans
  • Neural Pathways / anatomy & histology
  • Visual Perception / physiology*