Blood parameters are little affected by time of sampling after the application of ketamine in black howler monkeys (Alouatta pigra)

J Med Primatol. 2011 Oct;40(5):294-9. doi: 10.1111/j.1600-0684.2011.00474.x. Epub 2011 Mar 28.

Abstract

Background: Ketamine hydrochloride is an anesthetic commonly utilized to obtain biological samples in various non-human primates. Its application alters individual hematologic and biochemical values. The aim of this study was to analyze its effect on blood parameters of Alouatta pigra.

Method: We collected blood samples at 10 and 40 minutes after the application of ketamine in 12 adult female A. pigra living in free-ranging conditions.

Results: The analysis showed that 40 minutes after application of ketamine, the number of platelets, lymphocytes and concentration of phosphorus decreased; however, creatinine, cholesterol, triglycerides, and potassium values increased.

Conclusions: Our results suggest that ketamine appears to have little effect on the hematology and blood biochemistry of Alouatta pigra females with respect to those reported for other non-human primates. It is also important to consider the elapsed time after their application when taking blood samples for proper interpretation of the hemogram of Alouatta pigra females.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alouatta / blood*
  • Anesthetics, Dissociative / administration & dosage*
  • Animals
  • Blood Chemical Analysis
  • Cholesterol / blood
  • Creatinine / blood
  • Female
  • Ketamine / administration & dosage*
  • Lymphocyte Count / veterinary
  • Male
  • Mexico
  • Phosphorus / blood
  • Platelet Count / veterinary
  • Potassium / blood
  • Time Factors
  • Triglycerides / blood

Substances

  • Anesthetics, Dissociative
  • Triglycerides
  • Phosphorus
  • Ketamine
  • Cholesterol
  • Creatinine
  • Potassium