UV screening of ferulic acid-zinc basic salt nanohybrid with controlled release rate

J Nanosci Nanotechnol. 2011 Jan;11(1):413-6. doi: 10.1166/jnn.2011.3274.

Abstract

Ferulic acid (FA), an organic UV absorber and free radical scavenger, was intercalated into an inorganic zinc basic salt (ZBS) matrix to prepare a UV screening material. FA molecules were vertically oriented bilayer in the ZBS lattice with an expansion of approximately 22.7 angstroms along the c-axis. The FA-ZBS nanohybrid exhibited a superior UV-A approximately UV-B screening ability and an antioxidant activity that was comparable to that of a pure FA molecule. The in vitro release test showed the biphasic release of the FA molecules from the FA-ZBS nanohybrid that consisted of an initial burst, followed by a slow and sustained release.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biphenyl Compounds / chemistry
  • Coumaric Acids / chemistry*
  • Delayed-Action Preparations
  • Drug Stability
  • Nanocomposites / chemistry*
  • Nanocomposites / radiation effects*
  • Picrates / chemistry
  • Powder Diffraction
  • Spectrophotometry, Ultraviolet
  • Spectroscopy, Fourier Transform Infrared
  • Sunscreening Agents / chemistry*
  • Ultraviolet Rays
  • Zinc / chemistry*

Substances

  • Biphenyl Compounds
  • Coumaric Acids
  • Delayed-Action Preparations
  • Picrates
  • Sunscreening Agents
  • ferulic acid
  • 1,1-diphenyl-2-picrylhydrazyl
  • Zinc