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Review
. 2011;3(1):1-6.
doi: 10.4274/jcrpe.v3i1.01. Epub 2011 Feb 23.

Effects of environmental endocrine disruptors on pubertal development

Samim Özen  1 , Şükran Darcan
Affiliations
Free PMC article
Review

Effects of environmental endocrine disruptors on pubertal development

Samim Özen et al. J Clin Res Pediatr Endocrinol. 2011.
Free PMC article

Abstract

The onset and course of puberty are under the control of the neuroendocrine system. Factors affecting the timing and regulation of the functions of this system may alter the onset and course of puberty. Several environmental endocrine disruptors (EDs) with significant influences on the normal course of puberty have been identified. Numerous animal and human studies concerning EDs have been conducted showing that these substances may extensively affect human health; nevertheless, there are still several issues that remain to be clarified. In this paper, the available evidence from animal and human studies on the effects of environmental EDs with the potential to cause precocious or delayed puberty was reviewed.

Keywords: endocrine disruptors; pubertal development; puberty.

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