Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 14 (1), 13-7

Iodine, Iodine Metabolism and Iodine Deficiency Disorders Revisited


Iodine, Iodine Metabolism and Iodine Deficiency Disorders Revisited

Farhana Ahad et al. Indian J Endocrinol Metab.


Iodine is a vital micronutrient required at all stages of life; fetal life and early childhood being the most critical phases of requirement. Diet is the sole source of iodine, which in turn is dependent upon the iodine content of water and soil. Iodine is metabolized in the human body through a series of stages involving the hypothalamus, pituitary, thyroid gland and blood. Recent advances in physiology and molecular science have revolutionized our understanding of iodine metabolism at the cellular and sub-cellular level. This in turn has improved our knowledge of Iodine Deficiency Disorders (IDD), their prevention, management and control. This article makes an attempt to revisit this important topic in light of recent advances and provides a comprehensive account of the subject.

Keywords: IDD; Iodine; iodine deficiency; iodine metabolism.


Figure 1
Figure 1
Synthesis and Release of thyroid hormones
Figure 2
Figure 2
Causes of iodine deficiency disorders

Similar articles

See all similar articles

Cited by 16 articles

See all "Cited by" articles


    1. Dhaar GM, Robbani I. Foundations of Community Medicine. India: Reed Elsevier; 2008. Nutritional problems of mothers and children. pp. 272–280.
    1. Detels R, Holland WW, Mc Ewen HJ, Omenn GS. Oxford Textbook of Public Health. 3. Oxford University Press; 1977. Endocrine and metabolic disorders; pp. 1114–1115.
    1. Khurana I. Textbook of Medical Physiology. India: Reed Elsevier; 2006. Endocrinal System; pp. 710–715.
    1. Pal GK. Textbook of Medical Physiology. India: Ahuja Publishing House; 2007. Endocrine Physiology; p. 346.
    1. Patrick L. Iodine: Deficiency and therapeutic considerations. Altern MedRev. 2008;13:116–127. - PubMed