hmChIP: a database and web server for exploring publicly available human and mouse ChIP-seq and ChIP-chip data

Bioinformatics. 2011 May 15;27(10):1447-8. doi: 10.1093/bioinformatics/btr156. Epub 2011 Mar 30.


hmChIP is a database of genome-wide chromatin immunoprecipitation (ChIP) data in human and mouse. Currently, the database contains 2016 samples from 492 ChIP-seq and ChIP-chip experiments, representing a total of 170 proteins and 11 069 914 protein-DNA interactions. A web server provides interface for database query. Protein-DNA binding intensities can be retrieved from individual samples for user-provided genomic regions. The retrieved intensities can be used to cluster samples and genomic regions to facilitate exploration of combinatorial patterns, cell-type dependencies, and cross-sample variability of protein-DNA interactions.


Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Chromatin Immunoprecipitation*
  • DNA / metabolism
  • DNA-Binding Proteins / metabolism
  • Databases, Genetic*
  • Genome-Wide Association Study*
  • Humans
  • Internet
  • Mice
  • Neoplasms / metabolism
  • Oligonucleotide Array Sequence Analysis*
  • Software


  • DNA-Binding Proteins
  • DNA