Food allergy therapy: is a cure within reach?

Pediatr Clin North Am. 2011 Apr;58(2):511-30, xii. doi: 10.1016/j.pcl.2011.02.010.


There is an unmet medical need for an effective food allergy therapy; thus, development of therapeutic interventions for food allergy is a top research priority. The food allergen-nonspecific therapies for food-induced anaphylaxis include monoclonal anti-IgE antibodies and Chinese herbs. The food allergen-specific therapies include oral, sublingual, and epicutaneous immunotherapy with native food allergens and mutated recombinant proteins. Diet containing heated milk and egg may represent an alternative approach to oral immunomodulation. Oral food immunotherapy remains an investigational treatment to be further studied before advancing into clinical practice.

Publication types

  • Review

MeSH terms

  • Allergens / immunology
  • Allergens / therapeutic use
  • Anaphylaxis / prevention & control
  • Antibodies, Anti-Idiotypic / therapeutic use
  • Child
  • Clinical Trials as Topic
  • Cooking
  • Desensitization, Immunologic / methods
  • Food Hypersensitivity / therapy*
  • Humans
  • Immune Tolerance
  • Immunotherapy / methods
  • Medicine, Chinese Traditional
  • Probiotics


  • Allergens
  • Antibodies, Anti-Idiotypic
  • anti-IgE antibodies