Can UV exposure reduce mortality?

Cancer Epidemiol Biomarkers Prev. 2011 Apr;20(4):582-4. doi: 10.1158/1055-9965.EPI-10-1255.

Abstract

A Swedish cohort analysis in this issue (1) demonstrates a significant reduction in all cause mortality and in cardiovascular mortality associated with several measures of sun exposure. In addition, ultraviolet exposure from tanning beds is associated with a significant increase in all cause mortality and cancer mortality. A potential explanation for the protective association is that UV exposure results in high levels of serum vitamin D which may improve survival. However, that explanation does not hold for ultraviolet exposure from tanning beds, which in this study is associated with a significant increase in all cause mortality and cancer mortality. Such a finding is curious and inconsistent with a vitamin D hypothesis. These results should impel investigators to study further the biology of ultraviolet radiation, both natural and artificial, and its health effects.

Publication types

  • Comment

MeSH terms

  • Cohort Studies
  • Environmental Exposure
  • Female
  • Humans
  • Male
  • Melanoma / blood
  • Melanoma / etiology
  • Melanoma / mortality*
  • Risk Factors
  • Skin Neoplasms / blood
  • Skin Neoplasms / etiology
  • Skin Neoplasms / mortality*
  • Sweden / epidemiology
  • Ultraviolet Rays*
  • Vitamin D / blood

Substances

  • Vitamin D