A comparative study of tea-tree oil versus benzoylperoxide in the treatment of acne
- PMID: 2145499
- DOI: 10.5694/j.1326-5377.1990.tb126150.x
A comparative study of tea-tree oil versus benzoylperoxide in the treatment of acne
Abstract
Tea-tree oil (an essential oil of the Australian native tree Melaleuca alternifolia) has long been regarded as a useful topical antiseptic agent in Australia and has been shown to have a variety of antimicrobial activities; however, only anecdotal evidence exists for its efficacy in the treatment of various skin conditions. We have performed a single-blind, randomised clinical trial on 124 patients to evaluate the efficacy and skin tolerance of 5% tea-tree oil gel in the treatment of mild to moderate acne when compared with 5% benzoyl peroxide lotion. The results of this study showed that both 5% tea-tree oil and 5% benzoyl peroxide had a significant effect in ameliorating the patients' acne by reducing the number of inflamed and non-inflamed lesions (open and closed comedones), although the onset of action in the case of tea-tree oil was slower. Encouragingly, fewer side effects were experienced by patients treated with tea-tree oil.
Similar articles
-
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne.Australas J Dermatol. 1992;33(3):131-4. doi: 10.1111/j.1440-0960.1992.tb00100.x. Australas J Dermatol. 1992. PMID: 1303072 Clinical Trial.
-
Tea tree oil in the treatment of tinea pedis.Australas J Dermatol. 1992;33(3):145-9. doi: 10.1111/j.1440-0960.1992.tb00103.x. Australas J Dermatol. 1992. PMID: 1303075 Clinical Trial.
-
A comparative study of isolutrol versus benzoyl peroxide in the treatment of acne.Australas J Dermatol. 1995 Feb;36(1):13-5. doi: 10.1111/j.1440-0960.1995.tb00917.x. Australas J Dermatol. 1995. PMID: 7763215 Clinical Trial.
-
Adapalene 0.1%/benzoyl peroxide 2.5% gel: a review of its use in the treatment of acne vulgaris in patients aged ≥ 12 years.Am J Clin Dermatol. 2011 Dec 1;12(6):407-20. doi: 10.2165/11208170-000000000-00000. Am J Clin Dermatol. 2011. PMID: 21967116 Review.
-
Management of comedonal acne vulgaris with fixed-combination topical therapy.J Cosmet Dermatol. 2018 Apr;17(2):227-231. doi: 10.1111/jocd.12497. Epub 2018 Jan 30. J Cosmet Dermatol. 2018. PMID: 29380941 Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
