Allogeneic stem cell transplant to eliminate germline mutations in the gene for CCAAT-enhancer-binding protein α from hematopoietic cells in a family with AML

Leukemia. 2011 Jul;25(7):1209-10. doi: 10.1038/leu.2011.64. Epub 2011 Apr 1.

Authors

M Stelljes, A Corbacioglu, R F Schlenk, K Döhner, M C Frühwald, C Rossig, K Ehlert, G Silling, C Müller-Tidow, H Juergens, H Döhner, W E Berdel, J Kienast, S Koschmieder

PMID: 21455213
DOI: 10.1038/leu.2011.64

No abstract available

Publication types

Letter

MeSH terms

Adult
Anticipation, Genetic
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
CCAAT-Enhancer-Binding Protein-alpha / genetics*
Child, Preschool
Combined Modality Therapy
Female
Germ-Line Mutation*
Hematopoietic Stem Cells / metabolism*
Hematopoietic Stem Cells / pathology
Humans
Leukemia, Myeloid, Acute / drug therapy
Leukemia, Myeloid, Acute / genetics
Leukemia, Myeloid, Acute / surgery*
Neoplasms, Second Primary / genetics
Neoplasms, Second Primary / surgery
Neoplastic Syndromes, Hereditary / genetics*
Pedigree
Peripheral Blood Stem Cell Transplantation*
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Recurrence
Salvage Therapy
Survivors
Transplantation, Homologous

Substances

CCAAT-Enhancer-Binding Protein-alpha