Rings in the neonate

Ir Med J. 2011 Feb;104(2):52-3.

Abstract

Neonatal lupus erythematosus (NLE) is an uncommon disease of the neonate. It is believed to be caused by the transplacental passage of maternal autoantibodies to the ribonucleoproteins (Ro/SSA, La/SSB or rarely U RNP) as these are almost invariably present in NLE sera. The most common clinical manifestations include cutaneous lupus lesions and congenital complete heart block. Hepatobiliary and haematologic abnormalities are reported less frequently. We describe a patient with cutaneous NLE to illustrate and raise awareness of the characteristic annular eruption of this condition. We also emphasize the need for thorough investigation for concomitant organ involvement and for maternal education regarding risk in future pregnancies.

Publication types

  • Case Reports

MeSH terms

  • Anti-Inflammatory Agents / administration & dosage
  • Female
  • Humans
  • Hydrocortisone / administration & dosage
  • Infant
  • Lupus Erythematosus, Systemic* / congenital
  • Lupus Erythematosus, Systemic* / diagnosis
  • Lupus Erythematosus, Systemic* / therapy

Substances

  • Anti-Inflammatory Agents
  • Hydrocortisone

Supplementary concepts

  • Neonatal Systemic lupus erythematosus