A case of zoster sine herpete of the trigeminal nerve

Bull Tokyo Dent Coll. 2011;52(1):47-51. doi: 10.2209/tdcpublication.52.47.

Abstract

Varicella-zoster virus reactivation causes zoster (shingles), a syndrome characterized by severe pain and a vesicular rash. The present report details a case of varicella-zoster virus reactivation of the maxillary and mandibular division of the right trigeminal nerve without evidence of vesicular rash (zoster sine herpete). It is difficult to identify owing to no typical clinical signs such as vesicular eruption. Zoster sine herpete of the trigeminal nerve, in particular, is rarely reported. In this case, the diagnosis was based on clinical findings and was supported by the demonstration of an immunoglobulin G antibody. Zoster sine herpete of the trigeminal nerve, in particular, should be considered in patients with severe facial pain over specific dermatomes, if they do not demonstrate appreciable findings of traumatic neuropathy, tumor or herpes zoster.

Publication types

  • Case Reports

MeSH terms

  • Amitriptyline / therapeutic use
  • Analgesics, Non-Narcotic / therapeutic use
  • Facial Pain / etiology*
  • Female
  • Humans
  • Immunoglobulin G / analysis
  • Middle Aged
  • Nerve Block
  • Trigeminal Nerve Diseases / diagnosis*
  • Trigeminal Nerve Diseases / drug therapy
  • Trigeminal Nerve Diseases / virology*
  • Virus Activation
  • Zoster Sine Herpete / diagnosis*

Substances

  • Analgesics, Non-Narcotic
  • Immunoglobulin G
  • Amitriptyline