Dissecting the Role of SALL4, a Newly Identified Stem Cell Factor, in Chronic Myelogenous Leukemia

Leukemia. 2011 Jul;25(7):1211-3. doi: 10.1038/leu.2011.65. Epub 2011 Apr 5.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Apoptosis
  • Blast Crisis / genetics
  • Blast Crisis / pathology
  • Cell Division
  • Disease Progression
  • Gene Expression Regulation, Leukemic
  • Gene Knockdown Techniques
  • Humans
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / pathology*
  • Leukemia, Myeloid, Chronic-Phase / genetics
  • Leukemia, Myeloid, Chronic-Phase / pathology
  • Mice
  • Mice, Inbred C57BL
  • Mice, Transgenic
  • Neoplasm Proteins / biosynthesis
  • Neoplasm Proteins / genetics
  • Neoplasm Proteins / physiology*
  • Neoplastic Stem Cells / cytology
  • Neoplastic Stem Cells / metabolism
  • Nuclear Proteins / genetics
  • Nuclear Proteins / physiology
  • Polycomb Repressive Complex 1
  • Proto-Oncogene Proteins / genetics
  • Proto-Oncogene Proteins / physiology
  • Radiation Chimera
  • Recombinant Fusion Proteins / physiology
  • Repressor Proteins / genetics
  • Repressor Proteins / physiology
  • Signal Transduction / drug effects
  • Transcription Factors / biosynthesis
  • Transcription Factors / genetics
  • Transcription Factors / physiology*

Substances

  • BMI1 protein, human
  • Neoplasm Proteins
  • Nuclear Proteins
  • Proto-Oncogene Proteins
  • Recombinant Fusion Proteins
  • Repressor Proteins
  • SALL4 protein, human
  • Transcription Factors
  • Polycomb Repressive Complex 1