Abstract
This article highlights the general mechanistic implications for transcriptional elongation based on the crystal structure describing Spt4/5 bound to the RNA polymerase clamp domain from the Cramer lab.
Publication types
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Comment
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Research Support, N.I.H., Extramural
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Review
MeSH terms
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Archaea / chemistry*
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Chromosomal Proteins, Non-Histone / chemistry*
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Crystallography, X-Ray
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DNA-Directed RNA Polymerases / chemistry*
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Escherichia coli Proteins / chemistry
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Peptide Elongation Factors / chemistry
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Protein Structure, Quaternary
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Transcription Factors / chemistry
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Transcriptional Elongation Factors / chemistry*
Substances
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Chromosomal Proteins, Non-Histone
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Escherichia coli Proteins
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NusG protein, E coli
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Peptide Elongation Factors
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Transcription Factors
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Transcriptional Elongation Factors
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SPT5 transcriptional elongation factor
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DNA-Directed RNA Polymerases