We present the history of the spa of Druskininkai which was founded in 1837. The professional and scientific career of Ksawery Wolfgang (-1864), an eminent physician of this spa, is described in the context of his importance for the development of Druskininkai. Wolfgang was a respected person in Druskininkai. He was the editor-in-chief and publisher of the magazine "Ondyna Druskienickich Zródeł" ("Ondine of Druskininkai Springs") and the author of the book "On salt springs in Druskininkai" (Vilnius 1841), as well as of several other publications. The properties of Druskininkai salt springs and their therapeutic effects in many diseases are discussed. Wolfgang was able to establish indications and contraindications to treatment in Druskininkai. Mention is made of the book "Druskininkai. A literary and medical essay" by Józef Ignacy Kraszewski and Ksawery Wolfgang (Vilnius 1848).