Lymphocytes bearing the T cell receptor gamma delta in human breast milk

Arch Dis Child. 1990 Nov;65(11):1274-5. doi: 10.1136/adc.65.11.1274-a.

Abstract

Lymphocytes bearing the T cell receptor gamma delta (TCR-gamma delta) were searched for in human early milk lymphocyte suspensions by two colour cytofluorimetric analysis. It was found that the proportion of TCR-gamma delta+ cells was twofold greater in colostrum than in either autologous or heterologous blood samples. Additional studies are needed to determine whether this particular subset of lymphocytes is involved in the lactation transmission of cellular immunity.

MeSH terms

  • Colostrum / immunology
  • Female
  • Humans
  • Milk, Human / immunology*
  • Postpartum Period / immunology
  • Pregnancy
  • Receptors, Antigen, T-Cell / analysis*
  • Receptors, Antigen, T-Cell, gamma-delta
  • T-Lymphocytes / immunology*

Substances

  • Receptors, Antigen, T-Cell
  • Receptors, Antigen, T-Cell, gamma-delta