Trastuzumab resistance: all roads lead to SRC

Nat Med. 2011 Apr;17(4):416-8. doi: 10.1038/nm0411-416.
No abstract available

Publication types

  • Comment
  • News

MeSH terms

  • Antibodies, Monoclonal / pharmacology*
  • Antibodies, Monoclonal, Humanized
  • Antineoplastic Agents / pharmacology
  • Breast Neoplasms / drug therapy
  • Breast Neoplasms / metabolism
  • Cell Line, Tumor
  • Drug Resistance, Neoplasm
  • Enzyme Activation
  • Female
  • Humans
  • Models, Biological
  • Receptor, ErbB-2 / metabolism
  • Trastuzumab
  • src-Family Kinases / metabolism*

Substances

  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Antineoplastic Agents
  • ERBB2 protein, human
  • Receptor, ErbB-2
  • src-Family Kinases
  • Trastuzumab