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, 14 (7-8), 866-9

In Vitro Amoebicidal Activity of Borage (Borago Officinalis) Extract on Entamoeba Histolytica

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In Vitro Amoebicidal Activity of Borage (Borago Officinalis) Extract on Entamoeba Histolytica

Catalina Leos-Rivas et al. J Med Food.

Abstract

Borage (Borago officinalis) is a plant with nutritional value that is also used in traditional medicine to treat gastrointestinal disease. This study investigated the amoebicidal activity of a methanol extract of borage. The 50% inhibitory concentration (IC₅₀) of the extract for Entamoeba histolytica was 33 μg/mL. The 50% lethal dose of the extract for brine shrimp was greater than 1,000 μg/mL. The IC₅₀ of the extract for Vero cells was 203.9 μg/mL. These results support the use of borage to prevent diseases associated with E. histolytica infection.

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