Papular-purpuric "gloves and socks" syndrome

J Am Acad Dermatol. 1990 Nov;23(5 Pt 1):850-4. doi: 10.1016/0190-9622(90)70302-x.


We report five cases of an acute, self-limiting dermatosis that has not been previously described. It consists of a pruritic edema and erythema of the hands and feet in a gloves-and-socks distribution and is associated with oral lesions and fever. The clinical course is characterized by the rapid development of petechial purpura and clearing of lesions within 1 to 2 weeks. The disease appears to affect only young and otherwise healthy persons and occurs mostly during the spring. The etiology is unknown but might be of infectious origin.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Clothing
  • Diagnosis, Differential
  • Drug Eruptions / etiology
  • Edema / pathology
  • Erythema / pathology
  • Female
  • Foot Dermatoses / etiology*
  • Foot Dermatoses / pathology
  • Hand Dermatoses / etiology*
  • Hand Dermatoses / pathology
  • Humans
  • Male
  • Syndrome