Diffusion MR imaging: basic principles

Neuroimaging Clin N Am. 2011 Feb;21(1):1-25, vii. doi: 10.1016/j.nic.2011.02.001.


From their origin as simple techniques primarily used for detecting acute cerebral ischemia, diffusion MR imaging techniques have rapidly evolved into a versatile set of tools that provide the only noninvasive means of characterizing brain microstructure and connectivity, becoming a mainstay of both clinical and investigational brain MR imaging. In this article, the basic principles required for understanding diffusion MR imaging techniques are reviewed with clinical neuroradiologists in mind.

Publication types

  • Review

MeSH terms

  • Acute Disease
  • Brain / pathology*
  • Brain Ischemia / diagnosis*
  • Brain Ischemia / pathology
  • Diffusion Magnetic Resonance Imaging / methods*
  • Diffusion Magnetic Resonance Imaging / standards*
  • Diffusion Tensor Imaging / methods
  • Diffusion Tensor Imaging / standards
  • Humans
  • Magnetic Resonance Imaging / methods
  • Magnetic Resonance Imaging / standards
  • Neurology / methods