A case of Henoch-Schoenlein purpura nephritis recurring after 3 years remission

Fukushima J Med Sci. 2010 Jun;56(1):50-6. doi: 10.5387/fms.56.50.

Abstract

Henoch-Schoenlein purpura (HSP) is a systemic disorder characterized by leukocytoclastic vasculitis involving the capillaries with IgA immune complexes deposition, and about 7% of patients with HSP experience recurrence. Most patients with recurring of HSP nephritis show a recurrence of clinical symptoms over a period ranging from 2 to 5 months, even after the disappearance of initial symptoms. Here we report a 9-year-old girl diagnosed with recurrent HSP and severe crescentic glomerulonephritis 3 years after complete resolution of the initial symptoms of HSP. Our case is unique in respect of the recurrence at more than 3 years after the complete resolution of initial symptoms, suggesting that careful followup is required in spite of improved renal symptoms in cases of HSP.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Female
  • Glomerulonephritis, IGA / diagnosis
  • Glomerulonephritis, IGA / etiology
  • Glomerulonephritis, IGA / therapy
  • Humans
  • IgA Vasculitis / diagnosis
  • IgA Vasculitis / etiology*
  • IgA Vasculitis / therapy
  • Plasmapheresis
  • Prednisolone / therapeutic use
  • Recurrence
  • Time Factors
  • Urokinase-Type Plasminogen Activator / therapeutic use

Substances

  • Prednisolone
  • Urokinase-Type Plasminogen Activator