Assignment of the human interferon-alpha receptor gene to chromosome 21q22.1 by in situ hybridization

J Interferon Res. 1990 Oct;10(5):515-7. doi: 10.1089/jir.1990.10.515.

Abstract

The human interferon-alpha receptor gene (IFN AR) has been assigned to the long arm of human chromosome 21 (report of the committee on the genetic constitution of chromosomes 20 and 21; Ref 1). The present report confirms the assignment and refines the mapping to the 21q22.1 band, using a cDNA probe for the human IFN AR gene and in situ hybridization to metaphase chromosomes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromosome Mapping / methods
  • Chromosomes, Human, Pair 21*
  • Down Syndrome / genetics
  • Humans
  • Interferon Type I*
  • Metaphase / genetics
  • Nucleic Acid Hybridization
  • Receptors, Immunologic / genetics*
  • Receptors, Interferon

Substances

  • Interferon Type I
  • Receptors, Immunologic
  • Receptors, Interferon