Fluoride release from a new glass-ionomer cement

Oper Dent. 2011 Jan-Feb;36(1):80-5. doi: 10.2341/10-219-LR. Epub 2011 Feb 21.


This study compared the amount and pattern of fluoride release from a new glass-ionomer-based material (nano-ionomer) with other restorative materials and correlated the surface area to volume of nano-sized filler with its capacity to release fluoride in the powder, more quickly increasing the fluoride. The materials evaluated were a nano-ionomer (Ketac N 100), a conventional glass-ionomer cement (GC Fuji II), a resin-modified glass ionomer cement (GC Fuji II LC), a compomer (Dyract F) and a fluoride-releasing resin composite (Tetric N Flow). A resin composite (Synergy Flow) served as the control. Ten specimens were fabricated from each of these materials using a customized metal mold. The fluoride release was measured every 24 hours for the first seven days, and on days 14, 21 and 28, a combination fluoride ion—selective electrode connected to an ion analyzer. The data was analyzed by one-way ANOVA and Tukey HSD test (p=0.05). An initial fluoride “burst effect” was seen with all of the materials, except for the control and compomer. The conventional glass-ionomer cement showed the highest fluoride release on the first three days. The nano-ionomer showed the maximum release of fluoride for the remaining days. A low constant level of fluoride release was seen from the compomer and fluoride-releasing resin composite throughout the study period.

Publication types

  • Comparative Study

MeSH terms

  • Analysis of Variance
  • Compomers / chemistry
  • Composite Resins / chemistry
  • Fluorides / analysis*
  • Glass Ionomer Cements / chemistry*
  • Materials Testing
  • Nanoparticles
  • Statistics, Nonparametric


  • Compomers
  • Composite Resins
  • Glass Ionomer Cements
  • Fluorides