Serratia marcescens bacteremia because of contaminated prefilled heparin and saline syringes: a multi-state report

Am J Infect Control. 2011 Aug;39(6):521-4. doi: 10.1016/j.ajic.2010.08.020. Epub 2011 Apr 13.

Abstract

A national outbreak of Serratia marcescens bacteremia because of contaminated prefilled heparin and saline syringes led to their recall. We evaluated the clinical impact of this outbreak in 57 patients at 3 centers. All patients were symptomatic and were treated with intravenous antibiotics with a fatal outcome in 1 patient.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / administration & dosage
  • Bacteremia / drug therapy
  • Bacteremia / epidemiology*
  • Bacteremia / microbiology
  • Child
  • Cross Infection / drug therapy
  • Cross Infection / epidemiology*
  • Cross Infection / microbiology
  • Disease Outbreaks*
  • Drug Contamination*
  • Female
  • Heparin
  • Humans
  • Male
  • Middle Aged
  • Serratia Infections / drug therapy
  • Serratia Infections / epidemiology*
  • Serratia Infections / microbiology
  • Serratia marcescens / isolation & purification*
  • Sodium Chloride
  • Syringes / microbiology
  • Treatment Outcome
  • United States / epidemiology
  • Young Adult

Substances

  • Anti-Bacterial Agents
  • Sodium Chloride
  • Heparin