Impact of a group mind/body intervention on pregnancy rates in IVF patients

Fertil Steril. 2011 Jun;95(7):2269-73. doi: 10.1016/j.fertnstert.2011.03.046. Epub 2011 Apr 15.


Objective: To determine if women who were randomized to a mind/body program before starting their first IVF cycle would have higher pregnancy rates than control subjects.

Design: Randomized, controlled, prospective study.

Setting: Private academically affiliated infertility center.

Patient(s): A total of 143 women aged≤40 years who were about to begin their first IVF cycle.

Intervention(s): Subjects were randomized to a ten-session mind/body program (MB) or a control group and followed for two IVF cycles.

Main outcome measure(s): Clinical pregnancy rate.

Result(s): Only 9% of the MB participants had attended at least one-half of their sessions at cycle 1 start. Pregnancy rates for cycle 1 were 43% for all subjects; 76% of the MB subjects had attended at least one-half of their sessions at cycle 2 start. Pregnancy rates for cycle 2 were 52% for MB and 20% for control.

Conclusion(s): MB participation was associated with increased pregnancy rates for cycle 2, prior to which most subjects had attended at least half of their sessions.

Trial registration: NCT01103973.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Boston
  • Chi-Square Distribution
  • Female
  • Fertilization in Vitro* / psychology
  • Humans
  • Infertility / complications
  • Infertility / psychology
  • Infertility / therapy*
  • Mind-Body Therapies*
  • Pregnancy
  • Pregnancy Rate*
  • Prospective Studies
  • Stress, Psychological / etiology
  • Stress, Psychological / therapy*
  • Treatment Outcome

Associated data