Near-infrared indocyanine green videoangiography for assessment of carotid endarterectomy

Acta Neurochir (Wien). 2011 Aug;153(8):1641-4; discussion 1644. doi: 10.1007/s00701-011-1018-1. Epub 2011 Apr 17.

Abstract

Background: Intraoperative fluorescence angiography with indocyanine green (ICG) as a tracer has recently been introduced as a novel technique for neurosurgery. We evaluated the feasibility and efficacy of near-infrared (NIR) indocyanine green (ICG) videoangiography for patients undergoing carotid endarterectomy (CEA).

Methods: Sixty patients (7 females, 53 males; mean age, 71.8 years) undergoing CEA for severe stenosis of the internal carotid artery (ICA) were included. During CEA, microscope-integrated intraoperative NIR videoangiographic recording was performed before and after the excision of the plaque and closure of the ICA.

Results: During the 60 CEA procedures, 60 consecutive ICG videoangiographic examinations were performed. All patients tolerated the intravenous injection of ICG well with no adverse effects. The videoangiographic study showed the blood stream of the ICA in all cases and the position of plaque in some cases.

Conclusion: Microscope-based ICG videoangiography is simple, and provides reliable and rapid intraoperative assessment of CEA.

Publication types

  • Clinical Trial

MeSH terms

  • Aged
  • Aged, 80 and over
  • Carotid Stenosis / diagnosis
  • Carotid Stenosis / surgery
  • Coloring Agents*
  • Endarterectomy, Carotid / methods*
  • Feasibility Studies
  • Female
  • Fluorescein Angiography / methods*
  • Humans
  • Indocyanine Green*
  • Male
  • Middle Aged
  • Outcome Assessment, Health Care / methods
  • Prospective Studies
  • Retrospective Studies
  • Spectroscopy, Near-Infrared / methods*
  • Video-Assisted Surgery / methods*

Substances

  • Coloring Agents
  • Indocyanine Green