A graphical interface for the FoldX forcefield

Bioinformatics. 2011 Jun 15;27(12):1711-2. doi: 10.1093/bioinformatics/btr254. Epub 2011 Apr 19.

Abstract

Summary: A graphical user interface for the FoldX protein design program has been developed as a plugin for the YASARA molecular graphics suite. The most prominent FoldX commands such as free energy difference upon mutagenesis and interaction energy calculations can now be run entirely via a windowed menu system and the results are immediately shown on screen.

Availability and implementation: The plugin is written in Python and is freely available for download at http://foldxyasara.switchlab.org/ and supported on Linux, MacOSX and MS Windows.

MeSH terms

  • Computer Graphics*
  • Mutagenesis
  • Protein Conformation*
  • Protein Folding
  • Proteins / chemistry
  • Proteins / genetics
  • Software*
  • User-Computer Interface

Substances

  • Proteins