Uterine carcinosarcoma

Clin Obstet Gynecol. 2011 Jun;54(2):292-304. doi: 10.1097/GRF.0b013e31821ac635.


Carcinosarcoma is a rare but highly aggressive uterine malignancy. Pathologically, carcinosarcoma is a biphasic neoplasm composed of a mixture of malignant epithelial and mesenchymal components. A comprehensive approach for management is recommended with complete surgical staging to assess tumor dissemination followed by multimodal therapy with combinations of external beam irradiation or vaginal brachytherapy and systematic chemotherapy in patients with both early and advanced stage disease.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Carcinosarcoma / diagnosis
  • Carcinosarcoma / pathology*
  • Carcinosarcoma / therapy*
  • Chemotherapy, Adjuvant
  • Endometrial Neoplasms / diagnosis
  • Endometrial Neoplasms / pathology*
  • Endometrial Neoplasms / therapy*
  • Female
  • Humans
  • Radiotherapy, Adjuvant


  • Antineoplastic Agents