Appetizer administration stimulates food consumption, weight gain and leptin levels in male Wistar rats

Appetite. 2011 Aug;57(1):131-3. doi: 10.1016/j.appet.2011.04.001. Epub 2011 Apr 13.

Abstract

Appetizers based on different spices/herbs are highly acceptable but evaluation of their functionality needs more attention. The present study, investigated the effects of appetizers on food consumption, weight gain, and leptin levels in male Wistar rats. Three appetizers, namely ginger beverage, ajowan beverage, and karpurvalli beverage were administered to groups of rats. The fasting leptin levels ranged from 0.75 to 2.5 ng/ml, while weights were in the range of 147-201 g. Decreased (3.4-10.8%) leptin levels following the consumption of appetizers indicated their appetizing effect, with a greater reduction (p<0.05) for ginger beverage and karpurvalli beverage. Weight gain after 10 days was 7.68% in the control group whereas it was 11.20 and 13.26% in rats fed with ginger and karpurvalli beverages, respectively. However, food consumption was higher in all the appetizer groups than in the controls.

MeSH terms

  • Animals
  • Appetite / drug effects*
  • Appetite Stimulants / pharmacology*
  • Beverages
  • Body Weight
  • Eating*
  • Fasting
  • Food
  • Food Technology
  • Leptin / blood*
  • Male
  • Rats
  • Rats, Wistar
  • Spices
  • Weight Gain*
  • Zingiber officinale

Substances

  • Appetite Stimulants
  • Leptin