The proteome and interactome of Streptococcus pneumoniae phage Cp-1

J Bacteriol. 2011 Jun;193(12):3135-8. doi: 10.1128/JB.01481-10. Epub 2011 Apr 22.

Abstract

Mass spectrometry analysis of Streptococcus pneumoniae bacteriophage Cp-1 identified a total of 12 proteins, and proteome-wide yeast two-hybrid screens revealed 17 binary interactions mainly among these structural proteins. On the basis of the resulting linkage map, we suggest an improved structural model of the Cp-1 virion.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Gene Expression Regulation, Viral / physiology*
  • Genome, Viral
  • Protein Binding
  • Proteome*
  • Proteomics / methods
  • Streptococcus Phages / classification
  • Streptococcus Phages / genetics
  • Streptococcus Phages / metabolism*
  • Streptococcus pneumoniae / virology*
  • Viral Proteins / genetics
  • Viral Proteins / metabolism*

Substances

  • Proteome
  • Viral Proteins