Fatal complication after thrombin injection for post-catheterization femoral pseudoaneurysm

Thorac Cardiovasc Surg. 2011 Sep;59(6):372-5. doi: 10.1055/s-0030-1270837. Epub 2011 Apr 26.


Femoral artery pseudoaneurysm (FAP) is one of the most common vascular complications after cardiac and peripheral angiographic procedures. Ultrasound-guided thrombin injection is the standard procedure for the treatment of FAP. Complications such as thrombotic events with leg ischemia after thrombin leakage into the femoral artery or immunogenic consequences are rare. Our experience indicates the need for caution when treating FAP, as severe complications can occur after thrombin injection in a femoral pseudoaneurysm, leading to a fatal event.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Aneurysm, False / diagnostic imaging
  • Aneurysm, False / drug therapy*
  • Aneurysm, False / etiology
  • Catheterization, Peripheral / adverse effects*
  • Fatal Outcome
  • Female
  • Femoral Artery*
  • Humans
  • Injections, Intralesional
  • Thrombin / administration & dosage
  • Thrombin / adverse effects*
  • Tomography, X-Ray Computed
  • Treatment Outcome


  • Thrombin