Evaluation of cochlear involvement by transient evoked otoacoustic emission test in children with Crimean-Congo hemorrhagic fever

Int J Pediatr Otorhinolaryngol. 2011 Jun;75(6):858-60. doi: 10.1016/j.ijporl.2011.03.027. Epub 2011 Apr 27.


Objective: The aim of this study was to investigate cochlear involvement in child patients with Crimean-Congo hemorrhagic fever (CCHF) disease.

Methods: Twenty-eight CCHF disease patients (56 ears) and 26 sex- and age-matched healthy control subjects (52 ears) were included in the study. Pure-tone audiometry at frequencies 0.25, 0.5, 1, 2, 4, and 6 kHz, immittance measures including tympanometry and acoustic reflex testing, and transient evoked otoacoustic emission (TEOAE) testing were performed in the patients and controls.

Results: The proportion with a result of 'fail' for the TEOAE test in the CCHF patients was not statistically significant from the control group (p>0.05).

Conclusions: CCHF disease does not impair cochlear function in children. The clinical course of CCHF among children seems to be milder than in adults.

MeSH terms

  • Adolescent
  • Age Factors
  • Audiometry, Evoked Response
  • Audiometry, Pure-Tone
  • Case-Control Studies
  • Child
  • Cochlea / physiopathology*
  • Cohort Studies
  • Female
  • Hemorrhagic Fever, Crimean / complications
  • Hemorrhagic Fever, Crimean / physiopathology*
  • Humans
  • Male
  • Otoacoustic Emissions, Spontaneous / physiology