Impact of prenatal diagnosis and therapy on neonatal surgery

Semin Fetal Neonatal Med. 2011 Jun;16(3):130-8. doi: 10.1016/j.siny.2011.03.007. Epub 2011 May 6.


The field of neonatal surgery is now inextricably linked to the field of obstetrics. Neonatologists and surgical specialists experienced with the postnatal management and outcomes of infants with various disorders now look in utero along with obstetricians and fetal medicine specialists to characterize the development and well-being of fetuses with congenital anomalies with a goal to optimize fetal, perinatal and postnatal management. The purpose of this article is to examine how prenatal diagnosis and therapy has influenced neonatal surgery. An overview of prenatal diagnosis and the evolution of fetal therapy are provided. In addition, we review the impact of prenatal diagnosis and therapy on the management and outcomes of infants with specific anomalies, including congenital lung malformations, sacrococcygeal teratoma, myelomeningocele, giant fetal neck masses, diaphragmatic hernia and congenital heart defects.

Publication types

  • Review

MeSH terms

  • Congenital Abnormalities / diagnosis*
  • Congenital Abnormalities / surgery*
  • Female
  • Fetal Diseases / surgery
  • Fetal Diseases / therapy*
  • Fetal Therapies / trends*
  • Humans
  • Infant, Newborn
  • Infant, Newborn, Diseases / surgery*
  • Male
  • Pregnancy
  • Prenatal Diagnosis / trends*