The microbial-mammalian metabolic axis: beyond simple metabolism

Cell Metab. 2011 May 4;13(5):489-90. doi: 10.1016/j.cmet.2011.04.005.


The microbiome heavily influences the metabolism of its host. In this issue of Cell Metabolism, Donohoe and colleagues demonstrate that microbial butyrate, used as a fuel metabolite, prevents autophagy in colonocytes, showing that the microbial-mammalian metabolic axis goes beyond simple metabolism.

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