[The safety of selective serotonin reuptake inhibitors: hemostasis]

Vestn Ross Akad Med Nauk. 2011:(3):32-6.
[Article in Russian]


The literature data of the reaction of haemostatic system to antidepressants from the group of selective inhibitors of serotonin reuptake are summarized. The development of haemorrhagic complications is analyzed. The risk/benefit ratio is estimated for the treatment of depression in patients with acute myocardial infarction and stroke. A differential approach to indication of antidepressants is substantiated for the treatment of comorbid depressive disorders in different types of somatic pathology.

Publication types

  • Review

MeSH terms

  • Antidepressive Agents / adverse effects*
  • Contraindications
  • Depression / complications
  • Depression / drug therapy
  • Hemorrhage / chemically induced*
  • Hemostasis / drug effects*
  • Humans
  • Myocardial Infarction / complications
  • Selective Serotonin Reuptake Inhibitors / adverse effects*
  • Stroke / complications


  • Antidepressive Agents
  • Serotonin Uptake Inhibitors